Pain Patients with Psychiatric Disorders Reduce Opioid Efficacy, Increase Abuse Risk

by / Saturday, 30 January 2016 /

Opioids are often prescribed to treat chronic lower back pain, but patients with comorbid psychiatric disorders such as depression and anxiety could experience significantly less pain relief with this therapy and may be more likely to abuse their medication.

In a study published in Anesthesiology, Ajay Wasan, MD, and colleagues conducted a prospective cohort study of 55 chronic lower back pain patients with low-to-high levels of depression or anxiety symptoms. The patients were prescribed oral morphine, oxycodone, or placebo for pain as needed for six months; pain levels and daily doses were recorded by patients.

Patients with high levels of depression or anxiety had 50% less improvement in back pain and were 75% more likely to abuse opioids. They also experienced increased side effects compared to those with low levels of depression or anxiety symptoms.

Wasan stated that these results emphasize the importance of identifying psychiatric disorders prior to opioid therapy as part of a multimodal treatment plan. It is essential to treat conditions early, preferably prior to lower back pain becoming chronic, as successful treatment of psychiatric disorders may boost pain relief and lower the risk of opioid abuse.

Integrity Life Sciences delivers a multitude of orthotic treatment options to address one of the most costly systemic ailments in the world, chronic low back and neck pain. Our advanced solution begins with the Integrity Spinal Care System (ISCS). Our ISCS non-surgical spinal decompression therapy systems are engineered to provide pain relief for compressive and degenerative conditions of the spine. Specifically, conditions that may be treated include: neck pain and back pain associated with herniated discs, protruding discs, degenerative disc disease, posterior facet syndrome, and sciatica. It achieves these effects through decompression of intervertebral discs, that is, unloading due to distraction and positioning.

As a compliment to the ISCS, Integrity offers the very effective Integrity Gel Support Brace. Our advanced lumbar support brace is a fitting compliment to non-surgical spinal decompression therapy and was designed as an adjunct therapy for those suffering from back pain due to disc related conditions. The Integrity Gel Support Brace may be used with or without Integrity’s non-surgical spinal decompression systems and is an excellent treatment option for the patient to use at home.

In addition, Integrity Life Sciences has been exclusively granted the use of all of the technology, products, US Patent and Trademark Office’s assignments, logos and other forms of intellectual property that were created by Axiom Worldwide, Inc. The agreement specifically includes the flagship product DRX 9000, its family of products, and all of its derivatives such as the DRX9000C. Integrity offers support for these products, which includes: sales, maintenance services, and repairs.

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Elements as Published in Psychiatry Advisors